'de-Aramaicize' originates from the English prefix 'de-' (from Latin 'de-' meaning 'remove' or 'from'), combined with 'Aramaic' (from the name of the Aramaic language via Greek/Latin), and the suffix '-ize' (from Greek '-izein' via Latin/French meaning 'to make or cause').

'de-Aramaicize' is a modern English coinage formed by productive combination of morphemes ('de-' + 'Aramaic' + '-ize'); it does not descend from a single medieval English word but from these separate elements that entered English at different times.

Initially formed to mean 'to remove Aramaic elements'; over time its use has been confined to specialist contexts (linguistic, textual, liturgical) and retains that basic meaning.