'bothersomeness' originates from English, specifically from the adjective 'bothersome' formed from the verb 'bother' plus the adjectival suffix '-some' and the nominalizing suffix '-ness'.

'bothersome' developed from the verb 'bother' (late 16th century attested in English) combined with '-some'; 'bother' itself is of uncertain origin but has been suggested to be influenced by Irish 'bodhar' (meaning 'deaf' or 'dull') or dialectal sources, and the modern noun 'bothersomeness' was formed by adding '-ness' to 'bothersome'.

Initially 'bother' referred to disturbance or trouble (with shades of bewilderment or distress), and over time derivatives like 'bothersome' and 'bothersomeness' came to denote the quality of causing annoyance or inconvenience; the core sense shifted toward 'causing irritation or nuisance'.