bioavailability-reducing
|bi-o-a-vail-a-bil-i-ty-re-duc-ing|
🇺🇸
/ˌbaɪ.oʊ.ə.veɪ.ləˈbɪl.ə.ti rɪˈduː.sɪŋ/
🇬🇧
/ˌbaɪ.əʊ.ə.veɪ.ləˈbɪl.ɪ.ti rɪˈdjuː.sɪŋ/
lowering the amount available in the body
Etymology
'bioavailability-reducing' is a modern compound formed from 'bioavailability' + 'reducing'. 'bioavailability' combines the prefix 'bio-' from Greek 'bios' meaning 'life' with 'availability' (from Latin/French roots relating to being available), while 'reducing' is the present-participle form of 'reduce' from Latin 'reducere' meaning 'lead back' or 'bring back'.
'bioavailability' is a 20th-century technical formation from 'bio-' + 'availability' used in pharmacology; 'reduce' comes from Latin 'reducere' > Old French/Medieval Latin forms and entered English as 'reduce'. The compound 'bioavailability-reducing' is a descriptive technical coinage formed in recent scientific writing by joining these elements.
Individually, 'bio-' originally referred to 'life' and 'availability' to 'being available'; 'reduce' originally meant 'lead back' or 'make smaller'. Combined in modern usage, the compound specifically means 'causing a smaller fraction of a substance to be available in the body'.
Meanings by Part of Speech
Adjective 1
causing a decrease in bioavailability — i.e., reducing the proportion of a substance (often a drug) that reaches the systemic circulation and is available to have an active effect.
The formulation contained bioavailability-reducing excipients that lowered the drug's effective concentration in plasma.
Synonyms
Antonyms
Last updated: 2025/12/22 18:58