'balanopreputial' originates from New Latin/medical formation, specifically from Greek 'balanos' and Latin 'praeputium', where 'balanos' meant 'acorn' (used figuratively for the glans) and 'praeputium' meant 'foreskin'.

'balanopreputial' was formed in medical Latin from combining elements 'balano-' (from Greek 'balanos') + 'preputial' (from Latin 'praeputium' > 'preputialis'), and was adopted into English in the same combined form 'balanopreputial'.

Initially it meant 'relating to the glans (acorn) and the foreskin', and this core medical meaning has been retained in modern usage.