'atypically-combined' originates from the prefix 'a-' meaning 'not' or 'without', and 'typical', from Greek 'typikos', meaning 'conforming to a type', combined with 'combined', from Latin 'combinare', meaning 'to unite'.

'atypically-combined' evolved from the combination of 'atypical' and 'combined', reflecting a modern usage to describe non-standard combinations.

Initially, it meant 'not typically combined', and this meaning has largely remained the same in modern usage.