'asyngamic' originates from Greek and New Latin, specifically from the prefix 'a-' (Greek ἀ-) meaning 'not' and Greek 'syngamos' (συγγάμος) meaning 'joined in marriage' or literally 'joined together' (used for gamete fusion in biology).

'asyngamic' developed via New Latin/Neo-Latin forms such as 'asyngamicus' (formed from Greek elements) and was borrowed into English in scientific contexts to form the adjective 'asyngamic'.

Initially the components meant 'not joined' or 'not married together' in a general sense, but in scientific usage the term evolved to mean specifically 'not involving the fusion of gametes' (i.e., asexual reproduction).