'asporogenic' originates from Greek, specifically from the prefix 'a-' (privative) combined with 'sporogenic' derived from Greek 'spora', where 'a-' meant 'not' and 'spora' meant 'seed/spore', and the suffix '-genic' (from Greek 'gen-'/'gignesthai') meant 'producing'.

'asporogenic' developed in scientific/Neo-Latin and English by adding the privative prefix 'a-' to 'sporogenic' (from Greek 'spora' + '-genic'), producing the modern English scientific adjective 'asporogenic'.

Initially it meant 'not producing spores' in technical contexts, and this core meaning has largely been preserved in modern scientific usage.