'aspermia' originates from New Latin/medical formation ultimately from Ancient Greek, specifically from the elements 'a-' and 'sperma', where 'a-' meant 'without' and 'sperma' meant 'seed' or 'semen'.

'aspermia' developed from the Greek components 'a-' + 'sperma' into New Latin/medical coinages and was adopted into modern English as 'aspermia'.

Initially it meant 'without seed' in a general sense, but over time it narrowed to the medical meaning 'absence of semen at ejaculation'.