'ascogonidia' originates from New Latin, built from the combining form 'asco-' (from Greek 'askos' meaning 'bag' or 'sac') and 'gonidium' (from Greek 'gonos' meaning 'seed' or 'offspring'), used in biological terminology to denote sac‑borne reproductive units.

'ascogonidium' developed as a specialized New Latin/technical term in mycology from earlier classical elements: Greek 'askos' + Greek 'gonos' produced neo‑Latin coinages such as 'ascogonium' and 'gonidium', which were combined and adapted into the modern technical form 'ascogonidium' and its plural 'ascogonidia'.

Initially formed from elements meaning 'sac' and 'seed' to denote sac‑related reproductive units; over time it became a specific mycological term referring to the particular budded reproductive cells produced by an ascogonium.