'artificialize' originates from English, formed from 'artificial' + the verb-forming suffix '-ize'; 'artificial' ultimately comes from Latin 'artificialis' (from 'artificium'/'artifex') and the suffix '-ize' comes from Greek '-izein' via Latin and Old French.

'artificial' changed from Latin 'artificialis' to Old French 'artificiel' and then to Middle English 'artificial'; the modern English verb 'artificialize' was later formed by adding the productive suffix '-ize' to 'artificial'.

Initially, related forms meant 'made by skill or art' (from Latin roots meaning 'skill' + 'to make'); over time the core idea shifted to 'to make something artificial' as a verb when '-ize' was appended.