'arteriofibrosis' originates from modern medical New Latin/English formation, specifically from the combining form 'arterio-' (from Latin/Greek 'arteria' meaning 'artery') and 'fibrosis' (from Greek 'fibros' meaning 'fiber' with '-osis' indicating a pathological condition).

'arteriofibrosis' is a compound formed in recent medical usage by combining 'arterio-' + 'fibrosis' to describe fibrotic changes of arteries; it was coined in modern medical English rather than inherited directly from a single historical word.

Initially the components referred separately to 'artery' and a 'fibrous condition'; the compounded term has come to mean specifically the fibrous degeneration or scarring of arterial walls in pathological contexts.