'antisudoric' originates from the combining form 'anti-' (from Greek/Latin meaning 'against') plus Latin 'sudor' meaning 'sweat', with the adjectival suffix '-ic'.

'antisudoric' was formed in Modern/Medical English by combining the prefix 'anti-' with the Latin root 'sudor' (sweat) and the suffix '-ic' to create an adjective meaning 'against sweat'; similar formations appear in New Latin medical terminology.

Initially and historically it has meant 'opposing or preventing sweat'; this basic meaning has been retained in modern usage.