'Antipolo' originates from Tagalog, specifically the word 'tipolo' (the local name for a tree, Artocarpus blancoi); Spanish-era usage and local naming produced the form 'Antipolo'.

'Antipolo' changed from the Tagalog word 'tipolo' (referring to the tipolo tree) and through Spanish-era place-naming conventions became the modern place name 'Antipolo'.

Initially, it referred to the 'tipolo' tree; over time it evolved into the current meaning as the name of the town and later the city 'Antipolo'.