'antiegotistic' originates from Modern English, formed by the prefix 'anti-' (from Greek 'anti' meaning 'against') combined with 'egotistic' (from Latin 'ego' meaning 'I' with the suffix '-istic' from Greek '-istikos' meaning 'pertaining to').

'antiegotistic' was created in Modern English by attaching 'anti-' to the established adjective 'egotistic'. The element 'egotistic' developed from the Latin 'ego' through formations like 'egoism' and 'egotism' in the 18th–19th centuries, and '-istic' as an adjectival suffix came via Greek/Latin usage.

Initially it would have been understood simply as 'against egotism'; over time it retains that basic sense and is used to describe attitudes, behaviors, or positions that oppose self-centeredness.