'anopheline-related' is a modern English compound formed from 'anopheline' and 'related'. 'Anopheline' originates from New Latin 'Anopheles', ultimately from Greek 'anōphélēs', where the prefix 'an-' meant 'not' and the root 'ōphélēs/opheles' meant 'useful' or 'helpful'. 'Related' comes from Latin 'relatus' (past participle of 'referre') via Middle English, where 're-' meant 'back/again' and 'ferre' meant 'to carry/bring'.

'anopheline' developed from the New Latin genus name 'Anopheles' (used in scientific nomenclature), which itself comes from Greek 'anōphélēs' meaning 'useless' or 'harmful'; the adjectival English form 'anopheline' was later combined with the English adjective 'related' to form the compound. 'Related' entered English via Old/Middle French and Latin 'relatus', becoming the modern English participial/adjectival form.

Originally the Greek root conveyed a sense of 'not useful' or 'harmful'; through taxonomy it became the proper name 'Anopheles' for a mosquito genus and then 'anopheline' as an adjective meaning 'of or relating to Anopheles'. The compound 'anopheline-related' now specifically means 'connected with Anopheles mosquitoes' rather than the older general sense of 'not useful'.