'anhydremic' originates from New Latin medical formation based on Greek, specifically the elements 'an-' meaning 'without', 'hydōr' meaning 'water', and the suffix '-emia' meaning 'condition of the blood', with the adjectival suffix '-ic'.

'anhydremic' changed from the New Latin noun 'anhydrēmia' (British 'anhydraemia') to form the English adjective 'anhydremic' (also British 'anhydraemic').

Initially, it meant 'a state of lacking water in the blood/body,' and this sense has largely remained the same in modern medical usage.