'anhedonia-related' originates from Greek and English: the Greek elements 'an-' and 'hēdonē' ('an-' meant 'without' and 'hēdonē' meant 'pleasure') combined with English 'related' (ultimately from Latin 'relatus') meaning 'connected to'.

'anhedonia' entered medical English via modern Latin from Greek 'an-' + 'hēdonē'; 'related' derives from Latin 'relatus' → Old French/Medieval forms → Middle English 'relaten' → modern English 'related'. The compound phrase 'anhedonia-related' is a modern English formation combining the medical noun with the adjective 'related'.

Initially the Greek roots conveyed 'without pleasure'; in modern medical English 'anhedonia' denotes a clinical symptom. 'Anhedonia-related' has come to mean 'connected to or characteristic of that lack of pleasure'.