'anglophobe' originates from modern English combining forms, specifically the prefix 'Anglo-' meaning 'English' and the suffix '-phobe' from Greek 'phobos,' where '-phobe' meant 'one who fears' and 'phobos' meant 'fear'.

'anglophobe' changed from late 19th-century English patterned formations using 'Anglo-' + '-phobe' (modeled on words like 'xenophobe' and 'Francophobe') and eventually became the modern English word 'anglophobe'.

Initially, it meant 'a person who fears or hates the English or England', and this meaning has largely remained the same in modern usage.