'analgize' originates from 'analgesia' (from Greek), specifically the word 'analgēsia,' where 'an-' meant 'without' and 'algos' meant 'pain.' The suffix '-ize' means 'to make or become.'

'analgēsia' (Greek) was adopted into English as 'analgesia,' and the verb form 'analgize' was created by adding the suffix '-ize.'

Initially, it meant 'to make without pain,' and this meaning has remained consistent in modern usage, referring to rendering something insensitive to pain.