'amphetamine' originates from the chemical name 'alpha-methylphenethylamine', where 'alpha' refers to the position of the methyl group in the chemical structure.

'alpha-methylphenethylamine' was shortened to 'amphetamine' for ease of use in both medical and colloquial contexts.

Initially, it was used primarily for medical purposes, but over time it became known for its illegal use as a recreational drug.