'adrenalectomized' originates from the combination of 'adrenal' and 'ectomy', where 'adrenal' refers to the adrenal glands and 'ectomy' is a surgical term meaning 'removal'.

'adrenalectomized' changed from the medical term 'adrenalectomy' and eventually became the adjective form 'adrenalectomized'.

Initially, it meant 'having undergone adrenal gland removal', and this meaning has remained consistent in modern usage.