'acatalepsia' originates from Greek, specifically the word 'ἀκαταληψία' (akatalepsia), where 'a-' meant 'not' and 'katalēpsis' meant 'comprehension'.

'ἀκαταληψία' transformed into the Latin word 'acatalepsia', and eventually became the modern English word 'acatalepsia'.

Initially, it meant 'incomprehensibility', but over time it evolved into its current meaning of 'the belief that human knowledge is limited and certainty is impossible'.