6-O-beta-D-glucosidase
|6-O-be-ta-D-glu-co-si-dase|
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/sɪks oʊ ˈbeɪtə diː ˌɡluːkoʊˈsaɪdeɪz/
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/sɪks əʊ ˈbeɪtə diː ˌɡluːkəˈsaɪdeɪz/
enzyme removing glucose at the 6-O position
Etymology
'6-O-beta-D-glucosidase' originates from systematic biochemical/Neo-Latin nomenclature, composed of the locant '6-O' (indicating the oxygen at position 6), 'beta' from Greek 'beta' meaning 'second' (denoting the β-configuration), 'D' from Latin 'dexter' used as the D stereochemical series marker, and 'glucosidase' formed from 'glucoside' + the enzyme suffix '-ase' (the suffix '-ase' ultimately from the name 'diastase').
'glucosidase' developed from 'glucoside' (the glycoside of glucose) plus the enzymatic suffix '-ase'; biochemical systematic names like '6-O-beta-D-glucosidase' were later assembled in modern enzyme nomenclature to specify position (6-O), stereochemistry (β, D) and substrate specificity.
Initially enzyme names like 'glucosidase' meant an enzyme acting on glucosides; over time the naming convention became more systematic and specific, so modern forms (e.g. '6-O-beta-D-glucosidase') explicitly indicate the precise position and stereochemistry of the bond being hydrolyzed.
Meanings by Part of Speech
Noun 1
an enzyme that catalyzes the hydrolysis of 6-O-β-D-glucosides, cleaving the β-D-glucosidic bond at the 6-O position and releasing a D-glucose moiety from the substrate.
6-O-beta-D-glucosidase catalyzes the hydrolysis of the 6-O-β-D-glucosidic bond, releasing D-glucose.
Synonyms
Last updated: 2026/01/05 11:25